Menopause means the decline of ovarian function and the end of reproductive capacity. The decline in ovarian function is progressive and the concept of perimenopause is now used to describe this progressive process. Perimenopause is the period from the onset of endocrine, biological and clinical features associated with menopause until within one year of menopause. Two-thirds of women experience a range of symptoms due to the decline in ovarian function and decrease in sex hormones, called perimenopausal syndrome. During the first half of menopause, about half of women experience menstrual disorders, irregular menstrual cycles, long duration and increased menstrual volume. Although fertility is low and there is a possibility of unwanted pregnancy, attention should still be paid to contraception, and for those with abnormal bleeding, they should be alerted to the occurrence of endometrial cancer. The most common symptoms of perimenopause are hot flashes, bouts of redness of the skin on the face and neck, accompanied by baking heat, followed by sweating. There are also mental and neurological symptoms, such as emotional instability, agitation and irritability, anxiety and depression. Some women experience symptoms of urinary and reproductive tract, urinary incontinence, recurrent vaginitis, urinary tract inflammation, and vaginal dryness. In addition skin wrinkles increase, thinning, dryness, itching, hyperpigmentation, and mild hair loss. Postmenopausal women are also prone to atherosclerosis, myocardial ischemia, infarction, hypertension, stroke and other cardiovascular diseases and osteoporosis. Menopause is a physiological process that inevitably occurs in the course of every woman’s life. To pass this stage peacefully, women need to maintain a good state of mind, timely health care, regular medical checkups, and if symptoms are severe, hormone replacement therapy can be used after excluding contraindications.