Cranial defects should not be unfamiliar to us, as there are many risk factors that may lead to the occurrence of cranial defects, such as sudden traffic accidents, brain surgery and falling objects. If skull defect is not treated in time, it will bring more harm to the body, so patients must pay attention to it. In clinical practice, many patients with cranial defects report that they have obvious local distension and pain, often feel dizzy, headache, memory loss, etc. More serious patients also have brain tissue atrophy and cystic degeneration, etc. It can be seen that the danger of cranial defects is very great, and you should go to the hospital for cranial repair surgery in time after the occurrence of defects. However, it is important to choose the right material for the skull repair surgery, which will be more helpful for recovery. At present, most hospitals widely use titanium mesh material, which is not expensive, but has many defects and shortcomings, such as patients are sensitive to external hot and cold reactions after surgery; rejection will occur; there is pain; it will also affect the normal medical examination after surgery, etc. Titanium mesh materials are too many problems, in order to achieve a more ideal cranial repair effect, a new type of polyether ether ketone PEEK material has emerged, its thermal insulation, elasticity, strength, hardness, etc. are comparable to the autologous cranial bone, no need to worry about the occurrence of the above-mentioned problems after surgery, and can be personalized three-dimensional shaping according to the patient’s cranial data, excellent repair effect, is the current new trend of cranial repair. The cost of PEEK material is a little higher than previous materials, but its safety and effectiveness are unmatched by other materials. In addition, PEEK material is not commonly used in China, only a few hospitals can use PEEK material to carry out surgery, we this earlier in the use of this new material, experienced in carrying out PEEK skull repair plastic surgery, the results are ideal, safe and secure.