Dapoxetine take an hour bad effect should be based on specific circumstances, generally related to drug failure, drug resistance, aggravation of the condition, etc., may need to be under the guidance of the doctor for a different kind of drug treatment or the use of psychological and behavioral therapy, Chinese medicine treatment and other methods of treatment. 1. Drug failure: If Dapoxetine is stored in moisture, or the drug has expired and other reasons may lead to the loss of effect of the drug, this time under the guidance of the doctor to use the drug has not expired. 2. Drug resistance: If patients take Dapoxetine for a long time, it may lead to the development of drug resistance, when taken again, the effect is not good or no effect, can be under the guidance of the doctor to change the kind of drug treatment, such as paroxetine, fluoxetine and sertraline. 3. aggravation: if the patient’s condition of premature ejaculation is aggravated, only taking dapoxetine may not be able to relieve the symptoms, at this time under the guidance of the doctor to use behavioral therapy, traditional Chinese medicine treatment and other integrated methods of treatment, commonly used behavioral therapy methods are extrusion method, stop-movement method and functional-sexual therapy, traditional Chinese medicine treatment needs to be in the professional Chinese medicine practitioner after the identification of the evidence of the use of traditional Chinese medicine tonics. Dapoxetine take an hour effect is not good when you should promptly go to the hospital, follow the doctor’s instructions for treatment.