A bulge on the inside of the ankle may be caused by cysts, gout, rheumatoid arthritis and other diseases. Treatment should be based on the cause of the disease, and commonly used treatments include conservative treatments such as wearing a brace, medication such as non-steroidal anti-inflammatory drugs (NSAIDs), and surgical treatments. 1. Localized cysts: these patients may have increased exudation, leading to the formation of localized cystic masses. Conservative treatment, such as wearing a brace to stabilize the joint and using non-steroidal anti-inflammatory drugs (NSAIDs) such as diclofenac sodium, can be used in less severe cases. If conservative treatment is ineffective, or if the condition seriously affects the joint function, surgery can be performed. 2. Gout: Patients with gout may have localized painful masses. The disease can be controlled by adjusting lifestyle habits, medication and surgery to slow down the progression of the disease and control the condition. Non-steroidal anti-inflammatory drugs such as colchicine and etoricoxib are often used during acute attacks to improve the symptoms and pain of arthritis. In the remission period, uric acid-lowering treatment can be carried out by using urea excretory drugs such as benzbromarone, urea synthesis inhibiting drugs such as febuxostat, and urine alkalinizing drugs such as sodium bicarbonate. 3. Rheumatoid arthritis: this type of patients can be due to synovial hyperplasia, causing deformation of the joints, resulting in ankle bulging. It is often treated by general therapy, medication and physical methods. Commonly used drugs include anti-inflammatory and analgesic drugs such as celecoxib and glucocorticoids such as prednisone. If you find a bulge on the inner side of the ankle, you should go to the hospital in time, and with the help of the doctor’s diagnosis to clarify the cause of the disease, and then deal with it accordingly.