Negative genetic test for lung cancer means that common genetic mutations and abnormalities of lung cancer are not detected in the patient. Lung cancer is a cancer with certain hereditary susceptibility and family aggregation, and genetic changes play an important role in the occurrence of lung cancer. Currently, common clinical treatments for lung cancer include molecular targeted therapy, surgery, radiotherapy, chemotherapy, etc., among which molecular targeted therapy belongs to drug therapy. Molecular targeted therapy refers to drugs that are developed to target clear cancer-causing genes. Generally patients can determine whether there is a specific gene mutation and its mutation type through genetic testing for lung cancer. Negative genetic test for lung cancer indicates that there is no specific gene mutation and gene abnormality in the tested genes, so the effect of applying molecularly targeted drugs to treat lung cancer in lung cancer patients is not significant. When symptoms such as cough, hemoptysis and chest pain occur, one should seek medical treatment promptly.