Early detection of esophageal cancer

  Early detection, diagnosis and treatment of esophageal cancer can significantly improve the treatment effect and prolong the survival rate, among which early detection is the most important. It is usually believed that patients can have no discomfort in the early stage of esophageal cancer, and only with the development of the disease and the expansion of the tumor, patients gradually appear abnormal feelings. In fact, there are a series of symptoms in the early stage of esophageal cancer, which can be detected if patients can pay enough attention and go to hospital in time. According to the data of esophageal cancer survey, more than 90% of patients with early stage esophageal cancer have different degrees of self-conscious symptoms. The following symptoms should be highly valued when they appear: choking sensation in eating. This symptom can be mild at the beginning and occur intermittently. This is mainly because the tumor grows upward and protrudes from the mucosal surface of the esophagus, food irritates the superficial esophageal lesion and provokes a functional esophageal spasm resulting in choking sensation. Treatment with anti-inflammatory and antispasmodic drugs is often effective. However, this symptom may reappear shortly afterwards.  Pain behind the sternum or painful swallowing is present in about 50% of cases. The nature of the pain is usually pins and needles or burning. It is more pronounced with coarse, dry and harder foods. Esophagoscopy and surgical resection of fresh specimens reveal that some of the early esophageal cancer lesions are mainly mucosal erosions and superficial ulcers, and inflammatory infiltrates are often seen at the microscopic lesion sites. These pathomorphological and histological changes can explain the clinical appearance of painful symptoms.  About 30% of patients have a sensation of dryness and tightness in the pharynx which is associated with a change in the form of movement of the esophageal peristalsis to the lesion during feeding or swallowing of secretions. The effect on the peristalsis of the esophagus reflexively causes contraction of the pharyngoesophageal sphincter to produce abnormal sensations.  Foreign body sensation in the esophagus accounts for 15% to 20% of the sensation of foreign body in the esophagus, like vegetable leaves or food particles pasted on the esophageal wall, with the feeling of not being able to swallow. This may be related to irritation of the submucosal nerve plexus of the lesion.  Other symptoms include posterior sternal swelling and discomfort, fullness and light pain in the heart fossa, subxiphoid process or upper abdomen, slow passage and stagnant feeling of food, etc.  The above early symptoms of esophageal cancer are often intermittent and recurrent. One patient can have one or several symptoms and they are affected by diet, emotion, medication and other factors. Early symptoms can usually last for more than 3 months, and by the time they occur frequently and consistently, they are no longer early. If patient Wang had taken those conscious symptoms seriously in the early stages of his disease and went to the hospital for detailed examination, early diagnosis was possible and the prognosis was good; however, the early symptoms were ignored and the disease was dragged to an advanced stage.