Pediatric nocturnal bedwetting is a common phenomenon among children. As the nervous system continues to develop, the control of urination by the bladder in normal infants and children will develop naturally and no special treatment is needed. According to statistics, at least 50%; of 2-year-old children do not wet the bed at night, 80%; of 3-year-old children do not need to wet the bed, and occasional nighttime bedwetting in children younger than 5 years old is not an abnormal phenomenon. If unconscious urination after sleep occurs repeatedly in children over 4 years of age, up to 2 times a week or more and lasting for at least 6 months, and there is no such phenomenon in the waking state, such children should be regarded as abnormal and clinically become the original law nocturnal enuresis, commonly known as bedwetting, according to Western studies, about 15% of children aged 5 years;. 7% of children aged 10 years; suffer from this disorder, while adolescents around 20 years of age suffer from enuresis 1 -2%. The latest Hong Kong survey results show that about 4% of children at age 7 still suffer from nocturnal enuresis. For a long time, most parents and some doctors do not consider bedwetting as a disease and need special treatment. In fact, bedwetting can cause a lot of inconvenience and worry to parents and children. Studies have shown that long-term enuresis can have a negative impact on children. Children with enuresis lack self-confidence, have poor coping skills, lack the courage to interact with others, often feel shy inside, and avoid participating in normal social and group activities, such as camping and travel. At the same time, these children are prone to suspicious and timid psychology, which affects their normal ability and potential, and individual children are stubborn and even aggressive, while parents may be exhausted from taking care of their children for a long time, leading to anxiety and resentment and excessive blame and punishment, which adds to the psychological burden of the children. How does pediatric enuresis develop? The following factors are known to be involved; studies have shown that if one parent has the disorder, there is a 1 in 2 chance that the child will develop the disorder and the child will usually recover from the disorder by the time the parent stops wetting; some children with enuresis have reduced or unstable bladder capacity at night; others have increased nighttime urination due to insufficient production of antidiuretic hormones; and some children are excessively sleepy and difficult to wake up. Bedwetting is usually more common in boys than in girls. This shows that enuresis is the result of the interaction of multiple factors such as genetic factors, bladder function, and sleep status. In modern times, people are seeking a higher quality of life, and enuresis, as a long-neglected disease that has been plaguing people’s physical and mental health, should be taken seriously by parents and children. Investigative treatment for the disorder has been initiated in developed countries and regions, and most of them can be cured. There are two methods to make the cure rate reach 70-80%; one is to establish the conditioned reflex by waking up with an alarm clock and train the child to respond to the filling of the bladder, but it requires close cooperation between the child and parents for good patience; the other method is oral desmopressin acetate medication, which can achieve the treatment purpose by concentrating and reducing the production of urine, this method is easier for the child and parents to accept, and has been commonly used in foreign countries and received This method is more acceptable to children and parents, and has been commonly used abroad and received good results.