Amphotericin is the generic name of the drug and has no other aliases. The trade name and generic name are the same even if they are produced by different manufacturers. Amphotericin is a relatively common diuretic and is clinically cheaper. This drug is mainly used for its diuretic effect by correcting the secondary increase in aldosterone secretion. In addition, in the process of diuresis, it can also antagonize the effect of potassium excretion caused by other diuretics, so aminopteridine is often combined with hydrochlorothiazide and other diuretics in the clinic, which can not only reduce edema, diuretic effect, but also minimize the appearance of hypokalemia side effects. At present, aminopterin tablets are mainly used in the treatment of congestive heart failure, ascites caused by liver cirrhosis and lower limb edema caused by nephrotic syndrome in clinical practice. It should be noted that when combined with other diuretics, care should be taken to reduce the dose of this drug. When hyperkalemia occurs clinically, this drug should be promptly discontinued or banned to avoid serious side effects such as cardiac arrest.