Closed mouth acne on 15-year-old face can be relieved by general treatment, medication and other treatments. 1. General treatment: whiteheads acne patients need to keep the face clean, do not use irritating soap, and at the same time a reasonable diet, eat more vegetables and fruits, keep the mood happy, do not be anxious and nervous. 2. Drug therapy: patients can use topical retinoic acid cream to treat whiteheads, can regulate the surface keratin formation of cell differentiation, but also can achieve the dissolution of acne and anti-inflammatory effect, can be combined with fusidic acid, mupirocin ointment treatment. 3. Other treatments: patients can improve acne through fruit acid peeling, by reducing the adhesion of keratinocytes, accelerating the shedding and renewal of epidermal cells, regulating the secretion of sebaceous glands, with better therapeutic effects. All of the above treatments should be used under the guidance of a doctor, avoid self-medication. At the same time, patients need to develop good living and dietary habits to reduce the incidence of closed mouth acne.