There is no good way to bring down high lipoprotein a alone. Current research shows that PCSK9 inhibitors such as eloxizumab or aliskirenzumab have a certain effect on high lipoprotein a. Others, including improvement of lifestyle, dietary control, and the role of statin drugs, are not clear. High lipoprotein A is an independent risk factor for atherosclerosis, which may lead to coronary heart disease, cerebral infarction and other cardiovascular diseases. Improvement of lifestyle includes regular diet, low-salt and low-fat diet, light and diversified diet, and eating more fruits and vegetables in moderation; one should exercise in moderation, with aerobic exercise as the mainstay, including swimming, jogging, cycling, etc.; weight reduction in moderation, and control of body weight and body fat have some effect on the prevention of cardiovascular diseases, but the role of elevated lipoprotein a is limited at present. Lipoprotein a high should go to the hospital, the specific use of drugs need to follow the doctor’s instructions.