Whether Hepatitis B dna virus 4.02e+3 requires treatment needs to be examined and judged in conjunction with family history. If liver function is normal, there is no obvious cirrhosis, and there is no family history of cirrhosis or hepatocellular carcinoma, the patient can generally be observed; otherwise, antiviral therapy is needed. If the patient’s further examination reveals abnormal liver function, antiviral therapy needs to be started after other causes of abnormal liver function are ruled out. If the patient’s liver hardness or ultrasound examination suggests liver fibrosis, cirrhosis or hepatocellular carcinoma, antiviral therapy also needs to be started. Starting antiviral therapy is also recommended if the patient has a family history of liver cancer or cirrhosis and is over 30 years of age. If the patient’s liver function, liver stiffness, and liver ultrasound are normal and there is no family history of cirrhosis or liver cancer, antiviral therapy is not needed for the time being in this case. However, they should visit a specialist every 3 to 6 months for regular review, and once abnormalities are detected, treatment should be carried out in a timely manner.