Why should I get vaccinated? 99.7% of cervical cancers are caused by HPV infection. Who can need HPV vaccination? Although guidelines vary from country to country, the best age for vaccination that is currently accepted is for women aged 9-26 years: 1. Vaccination is recommended for women aged 9-26 years with or without a history of sexual intercourse. 2. Vaccination is also recommended for women older than 26 years old who have not had sex. 3. Vaccination is not recommended for women older than 26 years of age who are sexually active and have a regular sexual partner. 4. The U.S. Centers for Disease Control and Prevention (CDC) recommends that boys between the ages of 11 and 12 be vaccinated. Why does it discriminate against older women who have sex? 1. Women within the optimal injection age group are stratified by 15 years of age. 2. After HPV infection, 90% of women will naturally fade away without knowing it (about 1~2 years), so the international unified opinion on the effectiveness of vaccination for older women who have already had sex is LESS effective. However, the maximum age of vaccination abroad is 45 years. What is the difference between the various vaccines on the market? Currently there are bivalent, quadrivalent and nine-valent vaccines. They are currently not available on the mainland, but only in Taiwan, Hong Kong and Macau. 1.Bivalent Covers HPV 16 and 18: these two types of HPV cause about 70% of cervical cancer and 50% of cervical precancerous lesions; cause 60% of vaginal cancer and its precancerous lesions; cause 35-77% of vulvar cancer and 75%-80% of vulvar precancerous lesions. 2, quadrivalent Covering 6, 11, 16, 18: It is the addition of 6 and 11 to the bivalent, because 6 and 11 also cause 90% of acromegaly. But not quadrivalent is better than bivalent ah, because bivalent vaccine induced serum-neutralizing antibody titers of 16 is 2.3-4.8 times that of quadrivalent, while induced serum-neutralizing antibody titers of 18 is 6.8-9.1 times that of quadrivalent. 3.9-valent Scientists have put in a tough move: the super Saiyan of the vaccine world Covering 31, 33, 45, 52, 58 on top of quadrivalent. 31,33,45,52,58 cause an additional 19% of invasive cervical cancer. The efficacy of the vaccine depends on its effectiveness: 1. For people who are not infected with HPV: the preventive effect of bivalent for ≥CIN2 is 93%; the preventive effect of quadrivalent for ≥CIN2 is 97%~100%; the preventive effect of nine-valent for ≥CIN2 is 97%; 2. What if I get pregnant during the vaccination? The HPV vaccine requires 3 injections, so try to avoid pregnancy during the vaccination; if you get pregnant during the injection, don’t be nervous because there is no evidence that the HPV vaccine is harmful to the embryo; you can continue to complete the rest of the injection dose after the pregnancy is over or you are torn about whether to go to Hong Kong to do it, what should I do? No need for routine cervical physical examination after vaccination? Wrong, even after the vaccine is also to routine cervical physical examination; 1, because the preventive effect is not 100%; 2, in the ovulation period cervical local HPV antibody titer will drop, so still need to wear condoms; 3, more amazing is the use of compounded short-acting oral contraceptives women, the whole cycle of cervical local HPV antibody titer did not drop! Awesome, see again the magic of compounded short-acting oral contraceptives. Why should men get the HPV vaccine too? 1. HPV types 6 and 11 cause 90% of acromegaly in men and women; 2. HPV types 16 and 18 cause: 70-85% of penile cancer, anal cancer and their precancerous lesions, as well as oral cancer and throat cancer.