Eighty-year-old people do not have appetite do not want to eat may be functional dyspepsia, chronic gastritis, peptic ulcer and other causes, need to be given according to its cause to promote digestion, acid inhibition, gastric mucosa protection drugs and other medications. 1. Functional dyspepsia: slow gastric peristalsis leads to bloating and lack of appetite, which can be treated with drugs such as domperidone and mosapride to enhance gastric motility, combined with pepsin to promote digestion and increase appetite. 2. Chronic gastritis: chronic inflammation of the gastric mucosa affects the digestion of food, resulting in lack of appetite, can be given acid inhibitors such as omeprazole, pantoprazole and so on, combined with gastric mucosal protection drugs, such as aluminum thioglycollate and other drugs. 3. Peptic ulcer: if there is Helicobacter pylori infection, you can give omeprazole, amoxicillin, metronidazole, bismuth potassium citrate and other drugs. Eighty-year-olds have no appetite, do not want to eat, there may be oncological diseases, hypothyroidism and other diseases, it is recommended that timely medical care, identify the cause of the treatment as prescribed by the doctor, so as not to miss the condition.