Eyelid swelling when patients wake up from sleep may be caused by improper sleeping posture, drinking too much water before going to bed, conjunctivitis, blepharitis and other factors. 1. Physiological factors: If the patient sleeps in an improper posture at night, the eyelids are under pressure for a long time, which may lead to poor local blood circulation, resulting in eyelid swelling after waking up. If you drink a lot of water before going to bed at night, your kidneys may not be able to metabolize this water out of your body in time, thus leading to water retention in the body, which may also lead to eyelid edema after getting up from sleep. 2. Blepharitis: If the patient’s eyelid glands are infected by pathogenic bacteria, under the stimulation of inflammation, the patient may have red, swollen, painful, itchy eyes and other uncomfortable symptoms. 3. Conjunctivitis: When allergic patients are exposed to allergens such as duvet covers and pillowcases while sleeping, they may develop allergic conjunctivitis, which may cause swelling and itching of the eyes. It is recommended that in addition to eyelid swelling after waking up, there are other symptoms of discomfort patients timely consultation, assessment of the condition, and follow the doctor’s instructions for treatment.