In recent years, autologous fat granule injection grafting has been used in concert with prosthesis placement reconstructive surgery at home and abroad (especially in Korea) to repair a range of soft tissue defects, effectively enhancing the results of breast reconstruction and gaining increasing attention and popularity in the plastic surgery community. Advantages:The graft is autologous tissue, its biological properties are far superior to any artificial tissue substitute, allogeneic or xenogeneic material, and it has excellent radiation permeability and radiotherapy tolerance, and it is easy to obtain material, abundant tissue sources, easy to operate, safe and reliable, and achieves the dual purpose of liposuction and weight loss and obtaining soft tissue filler at the same time. There is no obvious scar in both the donor and recipient areas, the shape is uniform and natural, there is no projection on the body surface, the injection can be repeated, and it is easy to shape. The disadvantage is that the fat particles injected into the breast cannot establish 100% blood circulation and become viable, about 40% to 60% of the fat particles are absorbed and fibrotic, so the effect is not long-lasting, and the formation of fibrous hard nodes affects the screening of breast cancer to varying degrees. If a large amount of fat accumulates together and is too concentrated, it will lead to fat necrosis, dissolution and absorption due to insufficient blood supply, which will easily cause infection, pain and produce sequelae such as cysts, fibrosis or calcification, breast deformation and fat necrosis. The success or failure of fat particles implantation depends on the handling of the fat obtained by suction and the injection technique. The fat particles must be evenly distributed in all layers of tissue and rely on the surrounding tissue fluid and vascular nutrient penetration for viability. It should not be too much at a time, preferably no more than 100 ml ( unilateral).