The posterior circulation is supplied by the vertebrobasilar artery, which supplies the cerebellum, brainstem, posterior 2/5 of the cerebral hemispheres, etc. After injury, clinical symptoms such as vertigo, nausea, vomiting, ataxia, impaired balance, clumsy speech, and dysphagia can be manifested. Posterior circulation cerebral infarction is often induced by the dislodgement of emboli, so once formed within 4.5 hours of the thrombolytic window, it is recommended to give active intravenous thrombolytic therapy to promote revascularization, and after 24 hours of stabilization, give antiplatelet aggregation, lipid-lowering, plaque stabilization and other drugs. At the same time, we should give treatment to activate blood circulation and improve microcirculation. Actively control blood pressure, stabilize blood sugar, and adjust the diet to prevent further progression of the disease. The mortality rate and disability rate of posterior circulation acute large vessel occlusive cerebral infarction are high in acute cerebral infarction, and the prognosis is extremely poor. For patients who exceed the time window of intravenous thrombolysis, emergency interventional thrombolysis provides another active and effective treatment option for patients who are still within the time window of treatment. Of course, the earlier the time, the better the effect, because time is brain and time is life!