The average life expectancy of patients with small triplets of hepatitis B can basically reach the level of normal people. Patients with small triplets of hepatitis B do not need special treatment if their liver function is normal, and regular review is sufficient. If there is a familial history of cirrhosis or liver cancer and the patient is older than 30 years old, a liver aspiration biopsy is recommended. If the inflammation or fibrosis is grade 2 or higher, prompt antiviral treatment is required. The purpose of antiviral treatment for hepatitis B is mainly to inhibit viral replication, reduce infectiousness and reduce the incidence of cirrhosis and hepatocellular carcinoma. Therefore, patients with hepatitis B minor tri-positive only need regular review and timely treatment if there are indications for treatment, and their life expectancy is basically the same as normal people.