The phenomenon of Sumudjai refers to the phenomenon that diabetic patients have low blood sugar at night and high blood sugar before breakfast. In the 1930s, Sumudje discovered that excessive insulin dosage could lead to unstable blood glucose in diabetes, and when insulin dosage was reduced, the patient’s blood glucose would fall, so he proposed the maxim of “if there is hypoglycemia, there is hyperglycemia”, and thus called this phenomenon Sumudje reaction. The “Sumudje phenomenon” is characterized by low blood sugar at night and high blood sugar before breakfast, which is simply called “low and then high”. It is mainly due to the nocturnal hypoglycemic reaction caused by the overuse of oral hypoglycemic drugs or insulin, and the body increases the secretion of hormones (such as glucagon, growth hormone, cortisol, etc.) with the effect of raising blood glucose through the negative feedback regulation mechanism for its own protection, and the blood glucose appears to rebound up. Clinical symptoms: 1) frequent morning headache and nausea; 2) frequent nocturnal hypoglycemia; 3) lean body mass and low sugar intake; 4) large fluctuation of urine sugar and urine ketone bodies in routine urine examination; 5) uncontrolled hyperglycemia before breakfast after insulin dosage is increased; Response When the phenomenon of Sumujie occurs, you should know that you are hyperglycemic caused by hypoglycemia at this time. Therefore, do not consider increasing the amount of medication or insulin injection for the time being, but actively adjust the diet and exercise within the next few days, and actively analyze the causes of the Sumoje phenomenon to overcome it!