Pain in the kidney area with normal ultrasound examination may be due to physiological reasons, but usually can be relieved after resting, or it may be due to diseases of the locomotor system, such as chronic lumbar muscle strain, lumbar disc herniation and so on. Although urological diseases can also cause pain in the kidney area, they are usually accompanied by abnormal ultrasound results, so kidney stones, hydronephrosis, renal tuberculosis and other diseases are less likely. Chronic lumbar muscle strain is caused by aseptic inflammation after acute sprain of the lumbar region, local muscles, ligaments and other tissues are damaged and not treated in time, or long-term poor posture of the lumbar region, long-term overweight and so on. This kind of pain usually manifests itself as recurrent lumbar distension and soreness. The cause of lumbar disc herniation is the mutation of lumbar intervertebral discs, and the patients may not only feel lumbar pain when standing or walking, but also may be accompanied by sciatica, numbness of the lower limbs, etc. Imaging tests such as CT, X-ray, and MRI can be used to definitively diagnose the disease. If the patient has pain in the kidney area and the ultrasound examination is normal, it is recommended to go to a regular hospital in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or treatment under the guidance of the doctor.