The general manifestations of gout are hyperuricemia, recurrent acute arthritis, gout stones and chronic arthritis, and renal lesions.
1. Hyperuricemia: fluctuating or persistent hyperuricemia.
2. Recurrent acute arthritis: sudden onset of the disease at midnight or early in the morning, with severe pain in the joints; redness, swelling, heat, pain and dysfunction in the affected joints within a few hours; unilateral 1st metatarsophalangeal joints are the most common; the attack is self-limiting, and will be relieved within 2 weeks; it may be accompanied by fever.
3. Gout stone and chronic arthritis: gout stone is the characteristic clinical manifestation of gout, commonly found in the auricle, around the joints, as well as the eagle’s beak, Achilles tendon, patellar bursa and other places. Chronic arthritis is mostly seen in patients without standardized treatment, with asymmetric irregular swelling and pain in the affected joints, and a large number of gout stones deposited in the joints can cause joint bone destruction.
4. Renal lesions: renal involvement can be manifested as increased nocturia, low molecular proteinuria, leukocyturia, renal insufficiency, hypertension, edema, anemia and so on. Uric acid nephrolithiasis can also occur, manifested by renal colic, hematuria, dysuria, hydronephrosis, pyelonephritis or peripheral nephritis and other manifestations vary. In severe cases, acute renal failure may occur.
If the patient has the above discomfort, it is recommended to consult a doctor in time and follow the doctor’s instructions to standardize the diagnosis and treatment.