The sweaty hands, numb feet and stomach pain of a girl’s menstruation is considered to be premenstrual syndrome, which is associated with increased prostaglandin levels, psychiatric factors, ovarian hormone imbalance, neurotransmitter abnormalities, etc. The prostaglandin level will increase when a girl has her menstrual period. 1. Increased prostaglandin content: When a girl is menstruating, the endometrial prostaglandin content will increase, and this hormone will cause excessive uterine contractions, vascular spasms, stomach pain, and will also cause cardiovascular and digestive symptoms. 2. Mental factors: girls who do not know much about physiology and are unusually nervous during menstruation may also aggravate their existing symptoms. 3. Ovarian hormone imbalance: When girls first start menstruating, the development of the hypothalamic-pituitary-ovarian axis is not particularly mature, and hormone levels are not stable, which may also cause PMS. 4. Neurotransmitter abnormality: the concentration of opioid peptides decreases when a girl is menstruating, and opioid peptides mainly come from the adrenal medulla, gastrointestinal tract, sympathetic nerves, etc., and the withdrawal of endogenous opioid peptides may lead to endocrine, digestive and neurological symptoms. Girls who experience these symptoms with menstruation are advised to learn to relieve stress, stay happy, and keep warm. If the symptoms are obvious and persistent, it is recommended to consult a doctor, complete the relevant examinations, and follow the doctor’s instructions to actively treat the symptoms.