Pediatric craniofacial malformation syndrome (Hallermann-Streiffsyndrome) is also known as H-S syndrome, mandibular, ocular, facial, and craniofacial hypoplasia syndrome, mandibular, ocular, facial, and craniofacial hypoplasia, and sparse hair syndrome (dyscephaliaoculomandibularis- hypotrichosissyndrome), cephalofacial mandibular and ocular dysmorphism syndrome, congenital cataractacongenitahypotrichosissyndrome, congenital cataractacongenitahypotrichosissyndrome, Ullrieh-Fremety-Dohna syndrome, Frangois syndrome, Audry syndrome type I, Fremery-Dohna syndrome, etc. The syndrome is characterized by cephalofacial deformities, congenital cataracts, and hair thinning. The syndrome is often accompanied by other malformations, such as spinal deformities, osteoporosis, homogeneous dwarfism, and mental retardation. Prevention: Refer to the congenital disease prevention method. Prevention should run from preconception to prenatal: 1. Premarital physical examination in the prevention of birth defects play an active role in the size of the role depends on the examination items and content, mainly including serological examination (such as hepatitis B virus, syphilis spirochetes, HIV), reproductive system examination (such as screening cervical inflammation), general physical examination (such as blood pressure, electrocardiogram) and ask the disease family history, personal past medical history, etc., to do a good job of genetic disease Consultations. 2. Pregnant women should avoid hazardous factors as much as possible, including staying away from smoke, alcohol, drugs, radiation, pesticides, noise, volatile and harmful gases, toxic and harmful heavy metals, etc. Systematic screening for birth defects is required during prenatal care during pregnancy, including regular ultrasound, serological screening, and chromosomal testing if necessary. In case of abnormal results, it is necessary to clarify whether the pregnancy should be terminated; the safety of the fetus in the womb; whether there are sequelae after birth, whether they are treatable, and how they will heal. Practical measures should be taken to diagnose and treat the problem.