Society is progressing and people are becoming more health conscious. Annual medical checkups provide the necessary protection for people’s health. Blood tests are one of the most common tests, and in addition to routine blood tests and biochemical tests, the five hepatitis B tests are also an essential part of them. But do you really know the significance of the five tests for hepatitis B? We often say there is no antibody, “big three yang”, “small three yang” are what do you know? As we all know, China is a big country of hepatitis B. Hepatitis B has become one of the most common infectious diseases in China. It has a high incidence and is highly contagious, and the hepatitis B five, also known as hepatitis B two-and-a-half, is a serum marker test used to detect hepatitis B virus (HBV) infection, and is currently the most commonly used test in hospitals in China. It includes surface antigen (HBsAg), surface antibody (anti-HBsAb), e antigen (HBeAg), e antibody (anti-HBeAb), and core antibody (anti-HBcAb). The five tests for hepatitis B can determine whether a person is infected with hepatitis B or the specific circumstances of the infection. So what is the significance of each of the five tests for hepatitis B? 1, hepatitis B surface antigen (HBsAg): it appears earliest in the blood of a person infected with hepatitis B, with a high titer, signifying the presence of the hepatitis B virus. Therefore, when the result of this test is positive, the infection of hepatitis B virus can be confirmed. 2, Hepatitis B surface antibody (HBsAb): is a protective antibody, its positive indicates that has been infected with the hepatitis B virus, or vaccinated against hepatitis B, thus producing a protective antibody. “The positive surface antibody is a good thing, it means that there are antibodies to the hepatitis B virus in your body, so you basically won’t be “hepatitis B” anymore. 3, Hepatitis B e antigen (HBeAg): e antigen is a sign of hepatitis B virus replication. It can determine the size of the infectiousness of the virus. If the test shows positive, it means that the virus is actively replicating in the body, the amount of toxicity in the blood is large, and the infectiousness is strong. Therefore, a positive e antigen is definitely not a good thing. 4, Hepatitis B e antibody (HBeAb): e antibody shows positive, indicating that hepatitis B is relatively good, the replication of the virus has changed from active to relatively quiescent, the amount of toxicity in the blood is reduced, and the infectiousness is relatively reduced. 5, hepatitis B core antibody (HBcAb): it mainly reflects the situation of HBV virus replication in the liver, once infected or being infected may appear this positive. The five items of hepatitis B meaning, then we often say “big three yang”, “small three yang” and what is the meaning? The order of the five items on the hepatitis B test sheets of most hospitals is unchanged, from the top and bottom are hepatitis B surface antigen (HBsAg), hepatitis B surface antibody (HBsAb), hepatitis B e antigen (HBeAg), hepatitis B e antibody (HBeAb), hepatitis B core antibody (HBcAb). What we often call “major triple positive” refers to the positive items 1, 3 and 5 in the test list, that is, three positive hepatitis B surface antigen (HBsAg), hepatitis B e antigen (HBeAg), hepatitis B core antibody (HBcAb). This means that the patient is infected with acute or chronic hepatitis B. At this time, the virus is highly contagious and can be easily transmitted to other people. It is more likely to progress to chronic hepatitis B. A minor triple positive means that the test is positive for items 1, 4 and 5, i.e. hepatitis B surface antigen (HBsAg), hepatitis B e antibody (HBeAb) and hepatitis B core antibody (HBcAb). This also indicates that the patient is infected with acute or chronic hepatitis B. “Minor triplets” are usually transformed from “major triplets”. This means that the body has developed some immunity to the hepatitis B e antigen, which means that the condition is better than the major triplets and the hepatitis B virus is relatively less contagious. The company’s main business is to provide a wide range of products and services to the public. People like these two cases should go to the hospital in time to get the hepatitis B vaccine so that the body can produce antibodies so that it can effectively resist the hepatitis B virus. Regardless of whether one is infected with hepatitis B or not, we should have a preliminary understanding of the five hepatitis B tests as a routine medical examination. If you don’t have antibodies, you should get the hepatitis B vaccination in time. If you have hepatitis B infection, you need to go to the hospital for further examination so as not to miss the best time for treatment.