There is no research data to prove that Azithromycin is harmful to semen. Azithromycin is commonly used in the form of dry suspension, tablets, dispersible tablets, granules, injections, and capsules. It is an antibacterial drug and is mainly used for the treatment of acute pharyngitis, acute tonsillitis, sinusitis, otitis media, acute bronchitis, acute exacerbation of chronic bronchitis, and pneumonia caused by Mycoplasma pneumoniae, and has not yet been found to cause any damage to fertility or the fetus. Some patients may experience dyspepsia, gastrointestinal flatulence, headache, bronchospasm, abnormal taste, abdominal pain, nausea, itching, rash and other adverse reactions while taking azithromycin, which need to be stopped immediately, and are prohibited for azithromycin, erythromycin, and patients with hepatic insufficiency. It is recommended that patients under the guidance of a doctor, strictly comply with medical advice to use drugs, not blindly use drugs or unauthorized changes in drug dosage, so as not to cause adverse effects on the body, triggering the emergence of other diseases.