If kidney cancer after surgery if accompanied by H. pylori infection, it is necessary to decide whether to carry out H. pylori killing treatment according to the individual’s physical condition, surgical method and scope. If radical nephrectomy or kidney transplantation is done, generally speaking, the kidney function will be slightly decreased after surgery. It will be harmful to your body if you do H. pylori removal with antibiotic quadruple drugs. The drug needs to be metabolized by the liver and kidneys, so it is not suitable for drug removal treatment. Oral probiotics can be taken for 3~5 cycles to inhibit the living environment of H. pylori and achieve antibacterial purpose. If you are doing local resection of the tumor, there is usually no significant effect on renal function. Close monitoring should be carried out after the operation to avoid the impact on renal function. Anti-Helicobacter pylori can take two kinds of antibiotics orally, amoxicillin clavulanate potassium tablets, omeprazole capsules and clarithromycin. Usually the medication is used for about 7~14 days, and then stop the medication for one month for rechecking. If Helicobacter pylori infection occurs after kidney cancer surgery, you should seek medical treatment as soon as possible to avoid delaying the condition. Please strictly follow the doctor’s prescription and do not take medication by yourself.