Liver cancer (primary liver cancer) is a common cancer in China, and according to the census data, the annual mortality rate of liver cancer ranks third only after stomach cancer and lung cancer. The liver is the metabolic center of many important substances in human body, and it also has important functions such as detoxification, secretion and excretion, etc. Once cancer appears in the liver, it is extremely harmful to human health. Clinically, it is noted that patients with liver cancer have a history of acute hepatitis-chronic hepatitis-cirrhosis-liver cancer, which shows that hepatitis has an extremely close relationship with liver cancer. It is also noted in the domestic research on liver cancer that the proportion of hepatitis in the population in the high incidence area of liver cancer is high, and hepatitis B surface antigen (HbsAg)-positive patients are significantly higher than HbsAg-negative patients in liver cancer patients. Chronic hepatitis can also lead to liver cancer directly without passing through the stage of liver cirrhosis. I. How far are hepatitis B patients from liver cancer? Medical statistics show that more than 90% of primary liver cancers in China are HBsAg-positive hepatitis B patients, that is to say, persistent infection of hepatitis B virus is the main reason. If we carefully review the medical history of primary liver cancer, it is not difficult to find out that nearly half of the patients are so-called “healthy virus carriers”, and the most obvious characteristics of these patients are: 1) Laboratory tests are “major triple Yang” or “minor triple Yang”, and liver cancer is “minor triple Yang”. The most obvious characteristics of these patients are: 1) Laboratory tests are “major triple positive” or “minor triple positive”, but liver function is basically normal; 2) The condition is hidden before the discovery of liver cancer, and there is no obvious symptom, or even no signs such as discomfort in the liver area. This performance gives both doctors and patients an alarm: if hepatitis B patients do not standardize treatment in time, liver cancer may be just one step away! Only scientific and standardized treatment can effectively prevent hepatitis B from turning into liver cancer. Otherwise, if left unchecked, the continuous infection and replication of hepatitis B virus and the fibrotic lesions caused by inflammation will inevitably lead to cirrhosis and even the occurrence of liver cancer. How many liver cancers are caused by hepatitis B? In clinic, the average age of cirrhosis patients is 35 years old, and 6%-15% of cirrhosis patients will develop into liver cancer after 5 years. Among the cirrhosis and liver cancer patients in China, 80%-90% are hepatitis B virus carriers. Of course, not all people infected with hepatitis B virus will eventually develop into cirrhosis and liver cancer, the key is to control hepatitis B in time. Is minor triple positive more likely to cause cancer? “Minor triple positive” is generally acute hepatitis B virus infection tends to recover, chronic hepatitis B and chronic hepatitis B virus carriers. Because of its clinical symptoms are not obvious, easy to be ignored, so there is a greater potential danger to human health. In contrast, “triple positive” people with serious clinical symptoms, easy to be emphasized and treated, and transformed into “small triple positive” or other patterns, so the detection rate in primary liver cancer patients is much lower than “small triple positive” people. Therefore, the detection rate of primary liver cancer patients is much lower than that of “minor triple positive” patients. “If there are risk factors such as not paying attention to rest and alcohol abuse, it will aggravate the damage to the liver, gradually form cirrhosis, and eventually lead to primary liver cancer. What are the symptoms of hepatitis B to liver cancer? The main symptom is cirrhosis. Usually, liver cirrhosis will first become cirrhosis and then liver cancer will occur. There is no clinical manifestation in the early stage, but it can be found out by checking AFP. If the following situations occur, the patient should go to the hospital for examination as early as possible: 1. Pain in the liver area. More than half of the patients have this as the first symptom, which is mostly persistent dull pain, stabbing pain or swelling pain. Systemic and gastrointestinal symptoms. It is not easy to attract attention in the early stage, mainly manifested as weakness, emaciation, loss of appetite, abdominal distension, etc. Some patients may be accompanied by nausea, vomiting. Some patients may be accompanied by nausea, vomiting, fever, diarrhea and other symptoms. In the late stage, anemia, jaundice, ascites, swelling of the lower limbs, subcutaneous bleeding and cachexia appear. Hepatomegaly. It is the most common main sign of liver cancer in middle or advanced stage. In many cases, hepatomegaly or liver mass is the first symptom of hepatocellular carcinoma when the patient touches it by chance.