Whether a rat bite requires a vaccination should be analyzed on a case-by-case basis. After being bitten by a mouse, the most common situation is wound inflammation and infection, and the need for tetanus vaccination should be decided according to the wound damage. If the wound is deep and heavy, a tetanus vaccination is usually required. If the wound is minor and very superficial, the tetanus vaccine may not be given. For the severity of the wound, if you are unable to judge for yourself, you can visit the hospital for a doctor’s help to assess. After being bitten by a mouse in life, first flush the wound using running water or soapy water. Squeeze out as much blood as possible, and then disinfect the wound with iodophor or alcohol. Then go to the hospital and let the doctor determine if a tetanus vaccination is needed. In addition, other pathogens carried by rats, such as plague bacillus, hantavirus, and rat bite fever spirochetes, can be transmitted through rat bites, but because of their low incidence, the relevant vaccines are not routinely administered and are only given to personnel in infected areas, epidemic prevention workers, and relevant laboratory staff, and are not generally administered to the general population in non-infected areas. Therefore, after being bitten by a rat, you should pay attention to cleaning and disinfecting the wound in a timely manner, and observe the symptoms at home. Once symptoms such as fever, chills, diarrhea and facial flushing appear, you should seek medical treatment in a timely manner.