The so-called face-slimming injection is botulinum toxin, which can achieve the purpose of face slimming by blocking the nerve conduction of our facial muscles. Perhaps you have heard individual beauty salons or plastic surgery organizations claiming that their botulinum toxin is new or imported, and the effect can be maintained for two years, or even longer; there is also said that botulinum toxin face slimming injection three times can be permanently effective, the fact is really so? From the principle of the role of botulinum toxin, this statement is obviously misleading the beauty seekers. We know that when botulinum toxin is injected into the muscle layer of the human body, so that the muscle undergoes a temporary weakening or paralysis, to achieve the purpose of removing wrinkles and thinning the face, but the body will gradually metabolize this drug. This metabolic process is certain, about 3-6 months. However, it is also possible that the speed of nerve regeneration varies among individuals, which leads to differences in the effect and maintenance time of Botox treatment among different people. The average duration of effectiveness of Botox is 3-4 months, which may be slightly prolonged after several injections, but generally does not exceed one year. Moreover, domestic and imported botulinum toxin is not much difference in efficacy, the real imported botulinum toxin brand, that is, the United States of America Allergan company’s BOTOX, although imported botulinum toxin in the purification method and purity has the advantage of the time of the effect of domestic botulinum toxin and almost no difference. The effect of botulinum toxin is slowly apparent, about two weeks to a month or so after the injection began to show; usually three to six months after the effect will slowly disappear, then if you want to get the original effect, you have to receive another injection. Even after 3 or more injections, the effect cannot be fixed permanently and will disappear after a period of time. To summarize, the statement that “after 3 consecutive injections of Botox, the effect will be permanent and there is no need for further injections” is not tenable. In addition, under certain conditions, Botox may lead to the production of neutralizing antibodies, and then the use of Botulinum toxin type A will not be effective, so it is necessary to switch to Botulinum toxin type B and F. The way to prevent the body from developing antibodies is to inject a dose of less than 100 units per injection, and the interval between two injections is greater than 1 month. Although the effect is short-lived, the effect is exact, but it is not that any fat face type can be thinned by Botox treatment. For those fat faces with more subcutaneous fat, facial liposuction or removal of buccal fat cushion is needed to solve the problem; and for square faces with big bones in the jaw angle, bone grinding surgery is needed to solve the problem. When using Botox to remove wrinkles, generally crow’s feet, forehead lines, inner nasolabial lines and neck wrinkles can be removed, but it is most suitable for early, less obvious wrinkles and the skin is not very loose. If there is significant skin laxity and sagging, surgical wrinkle removal is required.