Patient: My father had symptoms of forgetting names and words in 2006, but he had a brain CT which did not reveal any obvious symptoms, so he did not pay attention to them. Now it is difficult to communicate verbally, and I can’t express myself clearly. For example, he does not know the meaning of eyes and ears. Loves sweets, has stealing behavior, does not get lost and can go out by himself. He started to take Advil, Sertraline, Nimodipine and Aspirin. By 10 years, the disease gradually worsened, and according to the doctor’s advice, I added meperidine, but it is still not effectively controlled. What kind of treatment should I take now? Doctor: After reading the description of the patient’s condition, it seems that the patient has decreased speech and behavior problems, and frontal lobe impairment is suspected. Patients with predominantly frontal lobe impairment currently have no approved treatment options, and treatment is difficult and requires careful selection of medication. Suggestion: Accompany the patient to the dementia specialist clinic for further consultation and treatment, bringing the medical records of previous visits and all ancillary tests (e.g. MRI films). Treatment recommendations: antipsychotics should be used with caution in patients with impaired frontal lobe function, and anti-dementia drugs should be used with great caution. The most commonly used dementia drugs, cholinesterase inhibitors (Anserine, Esnon, Galantamine), may not be indicated because the altered function of the cholinergic system is not particularly pronounced in patients with frontal lobe dementia.