There are many reasons for the sudden appearance of many small blisters on the hands (blisters), may be sweat herpes, tinea versicolor, etc., need to be in the doctor’s guidance of topical glucocorticoid drugs, antifungal drugs treatment. 1. Sweat herpes: is a special type of eczema, and local contact with irritants, infections, mental factors, etc., in the clinical treatment can be prescribed topical dinexed ointment, halomethasone ointment and other glucocorticoid drugs. 2. Ringworm: ringworm is caused by dermatophyte infection, which is mainly spread through direct contact or sharing items with patients, resulting in erythema, papules, blisters, flaking and other conditions on the hands. Patients can follow the doctor’s instructions to use topical antifungal drugs, such as clotrimazole cream, Butenafine hydrochloride cream and so on. However, this symptom alone is not enough to diagnose the disease, and may be caused by other factors. It is recommended that patients consult a doctor in time to clarify the cause and give targeted treatment, do not blindly self-medication.