Hypertensive patients usually regular oral antihypertensive drugs, blood pressure is stable, but some cases, blood pressure may still suddenly fluctuate, if the systolic blood pressure suddenly rises to 150mmHg, may be related to emotions, stress, weather, disease and other reasons. It is necessary to visit the cardiology clinic in time to check the cause and adjust the antihypertensive treatment. 1. Emotions: emotional excitement, anxiety, poor sleep at night, etc., which will affect the patient’s sympathetic nerves, sympathetic hyperactivity, easy to raise blood pressure. 2. Stress: some sudden illnesses, environmental stimuli, such as car accidents, bone fracture, acute myocardial infarction, etc., the patient’s pain is intense, discomfort is obvious, this stress will stimulate the patient’s sympathetic nervous system and renin and other endocrine systems, elevate blood pressure. 3. Weather: when the weather turns cold and the temperature drops suddenly, the blood vessels will contract, and some hypertensive patients will have elevated blood pressure. 4. Disease: patients who have renal failure, renal artery stenosis, adrenal hyperplasia, pheochromocytoma and other diseases, will be based on primary hypertension, secondary hypertension, then the blood pressure will be suddenly fluctuating higher than before. If the previous blood pressure is stable, suddenly increased, to timely and formal consultation, adjust the antihypertensive treatment.