If a patient has symptoms of headache and eye pain, the first thing to consider is that the patient has recently been under more stress at work, or has had less sleep or overworked, causing the patient to have migraine symptoms, and migraine patients can also have headache and eye pain. The patient’s headache symptoms will get better after sleep. Some patients may also experience headache and eye pain due to infectious diseases, such as epidemic hemorrhagic fever, and may also have symptoms of low fever, oliguria, and renal failure. Headache and eye pain can also be seen in patients with orbital neuralgia, which can be treated with oral nerve-nourishing medications if the patient has orbital neuralgia.