Lymphoplasmacytic lymphoma is the standard medical name for plasma cell lymphoma, which can be effectively relieved with regular treatment, but is difficult to be completely cured. Plasma cell lymphoma is a kind of non-Hodgkin’s lymphoma, generally speaking, belongs to the inert lymphoma, its disease progresses slowly. The five-year survival rate is still very high. However, age, serum albumin, and hemoglobin concentration are very strong prognostic factors that suggest whether plasma cell lymphoma will have a good prognosis. Drugs include cyclophosphamide, adriamycin, vincristine, and rituximab. Once diagnosed with plasma cell lymphoma, it is recommended to go to a regular specialized hospital in time for regular treatment under the guidance of a physician to avoid delay. Actively cooperate with the doctor for treatment, is expected to get a good expectation of the disease.