Liraglutide is a commonly used clinical hypoglycemic drug, which belongs to glucagon-like peptide-1 analogue, or GLP-1 analogue. The side effects of liraglutide mainly include the following: 1. Gastrointestinal reactions, liraglutide can delay gastric emptying, and gastrointestinal irritation symptoms such as epigastric discomfort, nausea, vomiting, diarrhea and abdominal distension can occur after injection, which can be improved with the extension of treatment time starting from small doses. 2. Pancreatitis, GLP-1 analogues may induce acute pancreatitis, so it should be avoided as much as possible in patients with previous history of acute pancreatitis. 3. 3. Hypoglycemia, liraglutide is a glucose concentration-dependent hypoglycemic agent, which means that it promotes insulin secretion to lower blood glucose only when blood glucose is elevated, but does not promote insulin secretion when blood glucose is normal or lowered, so the incidence of hypoglycemic events is very low when liraglutide is used alone, but when used in combination with insulin and sulfonylurea hypoglycemic agents, it can also cause However, when combined with insulin and sulfonylurea hypoglycemic drugs, it can also cause hypoglycemia, and hypoglycemic coma can occur in severe cases.