There is no best clinical treatment for patients with appendiceal fecolithiasis, which can generally be treated with medication and surgery according to the actual condition of the patient. 1. Medication: Appendiceal fecolithiasis is usually caused by the accumulation of intestinal contents due to factors such as bad living habits and improper diet. As fecal stone blockage can easily cause secondary appendicitis, early patients can use levofloxacin tablets, moxifloxacin hydrochloride tablets and other drugs under the guidance of the doctor for treatment. 2. Surgery: For patients with large fecaliths or unsatisfactory drug treatment, laparoscopic appendectomy, open appendectomy and other surgical methods can be adopted for treatment. Once the patient has appendiceal fecaliths, it is recommended to consult a doctor in time to avoid delaying the condition and causing complications such as diffuse peritonitis and appendiceal perforation.