The decision of what tumor markers to check for lung cancer needs to be based on the specific type of pathology. If it is lung squamous cell carcinoma, squamous cell associated antigen needs to be checked; if it is small cell lung cancer, neuron-specific enolase needs to be checked; if it is lung adenocarcinoma, carcinoembryonic antigen, CA19-9, and CA15-3’s can be checked. By measuring the values of these tumor markers, it can reflect the efficacy of lung cancer treatment, as well as the initial detection of tumor recurrence. Of course, if lung cancer is not yet confirmed, but only lung cancer screening, these tumor markers can be checked, and if they are significantly higher than normal, malignant tumor can be highly suspected in the body.