Secondary prevention of cerebral infarction

  Cerebral infarction has a high recurrence rate, and your priority now is to prevent recurrence. Secondary prevention is critical. The following recommendations for secondary prevention have been made based on a combination of current studies, namely, endarterectomy should be performed when carotid stenosis is greater than 70% and symptomatic, and different treatments should be chosen for stenosis between 50% and 69%, depending on individual circumstances. If the stenosis is less than 50%, surgery is not necessary. Patients with cardiogenic thrombosis should be anticoagulated with an INR of 2.5 (interval 2.0 to 3.0), except in patients with cardiac mucinous tumors or bacterial endocarditis. For those without indications for surgery or anticoagulation, antiplatelet therapy should be administered, with aspirin 100 mg/d or aspirin in combination with diclofenac sodium as the first choice. There are no clinical trials on how to dose aspirin for re-stroke. One recommendation is to switch to clopidogrel. If ischemia recurrence is still not prevented, switch to oral anticoagulation therapy. Either continue with aspirin, add dipyridamole, add clobetasol, switch to ceclopidine or clobetasol, or switch to an oral anticoagulant (warfarin) with an INR of 2.0 I3.