Gastroesophageal reflux disease (GERD) is the reflux of gastric contents or duodenal fluid into the esophagus resulting in symptoms such as heartburn, acid reflux, retrosternal burning pain, or complications such as esophageal strictures and ulcers, and clinically includes reflux esophagitis and endoscopy-negative GERD. About 7-15% of the population has reflux symptoms, and the incidence increases with age, more in men than in women. The prognosis of GERD is generally good, and the combined treatment of Chinese and Western medicine is an important means to prevent and treat GERD. The prevention of GERD should pay special attention to keep a relaxed mood, pay attention to the combination of work and rest; eat in moderation, avoid overeating, avoid spicy, sweet and sour diet, quit smoking and alcohol, avoid high fat, coffee, strong tea, chocolate and other irritating and spicy food; cautiously use drugs that are irritating to the esophageal mucosa. At the same time, it is necessary to strengthen physical exercise and enhance physical fitness to improve the body’s ability to resist disease. Obese people are advised to lose weight and the belt should not be too tight, one side increases abdominal pressure and aggravates reflux.