Patients with bitter mouth and stomach discomfort mainly consider diseases of the liver, bile and stomach systems, as follows: 1. Acute and chronic hepatitis: edema and thickening of the gallbladder wall, poor bile excretion can lead to stasis in the biliary system, bile and bilirubin backflow into the blood, causing skin itching and jaundice, bile backflow into the stomach and esophagus and cause bitter mouth, when acute and chronic hepatitis, accompanied by a decreased appetite, indigestion and other symptoms. 2. Biliary system diseases 2. Biliary diseases: such as acute cholecystitis, gallstones and biliary tumors can cause intrahepatic and extrahepatic bile obstruction, severe itching, jaundice, and bitterness in the mouth. 3. Digestive disorders: bile reflux is caused, and symptoms such as bitterness in the mouth can occur. When the above situation occurs, it is important to seek medical attention in a timely manner and conduct comprehensive examination and treatment under the guidance of a doctor so as not to delay the condition.