Transaminase high should first determine the cause of disease, according to cause transaminase elevation cause, take effective drug treatment. Generally commonly used drugs have compound glycyrrhizin capsule, water fly artichoke capsule, compound dichloroacetic acid diisopropylamine tablets, Yin gardenia yellow oral solution and so on. 1. Stay up all night, overwork: because the body is too tired, may cause the short-term transaminase to be high, generally through the sufficient rest can restore the transaminase to the normal level, generally do not need to take the medicine. 2. Viral hepatitis: in case of hepatitis B or C, aminotransferases will be elevated when the patient progresses to a certain degree, and the patient will take liver-protecting and antiviral medicines as prescribed by the doctor, such as entecavir dispersible tablets, adefovir capsules and other medicines to alleviate the condition. 3. Fatty liver: If the transaminase is elevated due to fatty liver, patients can take compound glycyrrhizin capsule, and in general, we should eat a light diet, and participate in more sports and physical exercise. 4. Drug hepatitis: generally because of taking hepatotoxic drugs caused by elevated aminotransferases, first of all need to stop taking the drug, and then follow the doctor’s instructions to take compound glycyrrhizin capsules and silymarin capsules and other drugs to protect the liver. 5. Alcoholic liver disease: if the patient excessive or long-term alcohol consumption, may also lead to alcoholic hepatitis, and then make the transaminase elevation, for this kind of patients should first quit drinking, and oral liver drugs, such as compound glycyrrhizin capsule, compound diisopropylammonium dichloroacetate tablets and so on. Drugs should be used under the guidance of a doctor, and it is recommended that timely hospital diagnosis and treatment, to clarify the cause of the standardized treatment.