Quetiapine and olanzapine both belong to the second generation of antipsychotic drugs, there are differences in their indications, caution, etc., should be based on the patient’s specific situation to choose the therapeutic drugs, there is no which one is better. Quetiapine for schizophrenia positive symptoms of the therapeutic effect is relatively weak, emotional symptoms have a certain efficacy, such as schizophrenia, bipolar disorder manic episodes and so on. It is forbidden for patients who are allergic to the components of quetiapine, and should not drive vehicles, operate machinery or work at heights while taking the drug. Olanzapine is used for acute and maintenance treatment of schizophrenia, prevention of relapse of bipolar disorder and adjuvant treatment of acute phase of mania. Olanzapine is used with caution in patients with hypersensitivity to the components of Olanzapine, narrow-angle glaucoma, prostatic hypertrophy, paralytic bowel obstruction, myelodysplasia, and a history of myelosuppression. Both quetiapine and olanzapine are associated with increased weight, abnormal blood glucose, dyslipidemia, more common sedative and anticholinergic effects, rare extrapyramidal reactions, elevated prolactin, and hypotension. If you want to take these two drugs, you should use the drug under the guidance of a professional doctor, not to judge the use of drugs on their own to avoid danger.