Steroids include salt corticosteroids and glucocorticoids, and briefly introduce the glucocorticoids that are commonly used in clinical practice. These drugs mainly affect the metabolism of sugar and protein in human body, and have strong anti-inflammatory effects and weak immunosuppressive effects. They are suitable for various shock, serious infection, autoimmune connective tissue diseases, sequelae of various inflammatory diseases, hypopituitary hypoplasia, adrenocortical insufficiency and other disorders, and are often used in combination with immunosuppressive drugs for rejection reactions after organ transplantation. Clinical glucocorticoids are short-acting, including hydrocortisone and cortisone; medium-acting, such as prednisone, methylprednisolone and trenbolone; and long-acting, such as betamethasone and dexamethasone. Improperly applied in clinical practice, hormonal drugs can have serious side effects. In order to treat certain diseases, hormones have to be used, and clinicians must strictly regulate the use of hormonal drugs according to the patient’s condition to avoid side effects and adverse consequences.