Whether anterior superior mediastinal nodule 13mm is serious or not cannot be generalized, the cause needs to be clarified, benign ones are not serious and malignant ones are more serious. Anterosuperior mediastinal nodule usually in 2cm belongs to the serious situation, while the anterosuperior mediastinal nodule 13mm belongs to the medium-sized tumors, causing this symptom is mainly enlarged lymph nodes, teratomas, thyroid lesions, thymoma and other reasons, need to consult the doctor in time, to clarify the cause of the disease. If it is lymphoma, thymoma and so on need to pay attention to, follow the doctor’s instructions for surgical treatment, chemotherapy, radiotherapy and other treatments. Diet should pay attention to eat more high-calorie, high-protein food such as eggs, chicken, milk, etc. Patients can do some moderate exercise such as walking, swimming, etc., and should pay attention to rest in daily life to avoid spicy and stimulating food, meanwhile, should quit smoking and drinking, and go to the hospital for physical examination on a regular basis. It is recommended that patients go to the hospital in time for examination, symptomatic treatment under the guidance of the doctor, while regularly going to the hospital for physical examination.