Low-grade intraepithelial neoplasia means atypical hyperplasia or heterogeneous proliferative lesions of the epithelial tissue of an organ, which are morphological changes that occur in the process of tumorigenesis.
Medically, intraepithelial neoplasia is classified into three grades, reflecting the process of malignant tumor development. Among them, grade 1 is mild atypical hyperplasia, grade 2 is moderate atypical hyperplasia, grades 1 and 2 are low-grade intraepithelial neoplasia, and grade 3 is equivalent to severe atypical hyperplasia or xenoproliferative or carcinoma in situ.
In general, most low-grade intraepithelial neoplasia does not transform into malignant tumors and may subside naturally or exist in the form of tumors. In contrast, high-grade intraepithelial neoplasia has the potential to become cancerous and requires prompt prevention.
If low-grade intraepithelial neoplasia is detected, it should be regularly reviewed and closely monitored.