Infantile hepatic hemangioendothelioma can be treated with hormone and interferon, and surgery is needed when necessary. Infantile hepatic hemangioendothelioma is a kind of hepatic vascular malformation disease, with a certain self-limiting, often with abdominal hepatomegaly or abdominal mass as the main clinical manifestations, for patients without clinical symptoms, conservative treatment can be chosen, given to the prednisone, α-interferon treatment, if necessary, can be used to cyclophosphamide and other drugs. However, patients with tumor symptoms need timely surgical resection, and if the tumor is too large to be surgically resected, hepatic artery embolization and liver transplantation can also be considered. However, surgical resection is more effective than hepatic artery ligation and liver transplantation. It should be noted that the above treatments should be carried out under the guidance of physicians, and should not be taken by oneself.