Early Down’s syndrome screening requires fasting. Early Down’s syndrome screening screens for the risk of congenital malformations, such as trisomy 21 and trisomy 18. It is performed between 11 and 13 weeks of pregnancy and requires a comprehensive assessment with reference to the woman’s age and number of weeks of pregnancy. If there is a high risk, non-invasive DNA or amniocentesis will be required to confirm the diagnosis. If a woman is over 35 weeks of age, she should stop having Down’s syndrome screening and needs to have noninvasive DNA for screening. After pregnancy, women need to strengthen their maternity checkups, and during pregnancy, they need to have early Down’s syndrome screening, noninvasive DNA, and ultrasound for major abnormalities. In addition, after pregnancy, it is important to pay attention to proper rest, keep your mood relaxed, avoid adverse stimuli such as smoking and alcohol, and increase nutrition appropriately to benefit the pregnant woman’s own nutritional supply and the normal development of the fetus.