Patients with type 2 diabetes should choose glucose-lowering drugs according to their blood glucose. 1. Metformin is preferred, it is the drug of choice recommended by the guidelines, generally the maximum amount of 2000mg per use, it can effectively inhibit hepatic gluconeogenesis and improve the sensitivity of muscle fat to insulin. 2. α-glucosidase inhibitors, representative drugs include acarbose, it is mainly used to lower blood glucose 2 hours after meals, some patients will have gastrointestinal reactions. 3. 3.Sulfonylurea glucose-lowering drugs, such as gliclazide, glimepiride and glipizide, mainly promote insulin secretion. 4.DPP-4 inhibitors, glucose-dependent glucose-lowering therapy, with better safety and no obvious side effects. 5.SGLT-2 inhibitors, which lower blood sugar by increasing renal sugar excretion, have protective effects on both heart and kidney.