Urine urine protein +- may be due to physiological, pathological factors, physiological factors generally do not require special treatment, pathological factors including glomerulonephritis, purpura, etc., can be treated by drugs, specific treatment varies from disease to disease. 1. Physiological factors: If you are tired, stay up late, exercise, etc., it is easy to appear physiological urinary protein, which can be manifested as urinary routine urinary protein +-, no need to carry out special treatment, and can relieve the uncomfortable symptoms after appropriate rest. 2. Pathological factors (1) glomerulonephritis: due to infection, drugs and other influences, so that the immune complexes deposited on the glomeruli, resulting in the body of the phenomenon of infection, and cause urinary protein +-, can be timely medical advice for anti-infection such as penicillin, hormones such as methylprednisolone and other treatments. (2) allergic purpura: sensitizing factors from the outside world, causing the body to produce a perverse reaction, can appear urine routine urine protein +- phenomenon, can follow the doctor’s instructions to use hormones such as dexamethasone tablets, regulating the body’s metabolism in order to improve the symptoms of the disease. Urine protein +- may also have other reasons, if the patient urine urine protein +- phenomenon, it is recommended to go to the hospital in a timely manner, to clarify the cause of the disease, in accordance with the doctor’s instructions for treatment.