Menstrual disorders in 45-year-old women may be a sign of perimenopause. It is recommended to check ultrasound and sex hormone six to see if there are abnormal changes in ovarian function, endometrial thickness, and uterine adnexa. If the endometrium is thick, a diagnostic curettage is also recommended to scrape out the endometrium for pathological examination. If the postoperative pathology results are benign, systematic postoperative menstrual regulation is recommended to standardize menstruation to smoothly pass through the perimenopause. If the pathology is problematic, you can actively cooperate with the doctor to avoid delaying the diagnosis and treatment of the disease. Attention should be paid to the regularity of menstrual flow, and if abnormalities occur they need to be promptly checked.