Changes in the intervertebral foramen and their significance

Lumbar degenerative scoliosis (LDS) is a common disease of the spine that occurs after skeletal maturity secondary to degenerative changes in the lumbar intervertebral discs and lumbar spine joints, with persistent low back pain and nerve root symptoms in the lower extremities as the main manifestations. With the aging of the population and the change of people’s lifestyle in modern society, degenerative lumbar scoliosis has gradually become an important disease affecting the quality of life of the elderly, and the number of consultations is increasing, and the trend is rising year by year, so degenerative lumbar scoliosis is also becoming a serious socioeconomic problem. Because of the advanced age of patients with degenerative lumbar scoliosis and the frequent combination of other degenerative lumbar spine diseases and other systemic diseases, the treatment of degenerative lumbar spine diseases is more complex than that of single degenerative lumbar spine diseases, and the surgical difficulties and risks are greater, which is a new challenge for spine surgeons and has attracted the attention of many scholars and become one of the new research hotspots. Patients with degenerative lumbar scoliosis often complain of pain in the lower back and legs, with an incidence of 60% to 85%, manifesting as soreness and pain in the lower back that lasts for a long time and is not easily relieved by drug therapy. Low back pain mostly occurs in the weight-bearing upright position and cannot be relieved by sitting or squatting, but can be significantly relieved by lying down, which is called “postural low back pain”. Some patients also have numbness and loss of muscle strength in the limbs, and some patients have loss of sensation and walking weakness in one or both lower limbs. Existing research suggests that it is not easy to determine the exact site of origin of the pain, and that scoliosis may be only one of the causes of the pain. The causes of degenerative lumbar scoliosis pain may include disc degeneration, trunk imbalance, lumbar instability, synovial joint hyperplasia, reduction in the volume of the spinal canal, foraminal stenosis, compression of the nerve roots on the concave side and strain on the nerve roots on the convex side, and strain on the paravertebral muscles due to scoliosis. The pathogenesis, the factors of lumbar pain and the characteristics of nerve root compression need to be further studied. The lumbar synovial joint is an important motor unit between the vertebrae, except for the intervertebral discs, and is closely related to the flexion and extension, rotation and other activities of the spine. The morphology and orientation of the synovial joints have an important impact on the direction and stability of spinal motion. More studies have shown that the lumbar synovial joint angle is associated with degenerative lumbar spine disease, but little research has been reported on its role in degenerative lumbar scoliosis. In the pathogenesis of degenerative lumbar scoliosis, it is still inconclusive whether the scoliosis is triggered by disc degeneration or by synovial joint degeneration, whether lumbar scoliosis aggravates the degeneration of the disc and synovial joint, or whether both are mutually influential. The lumbar intervertebral foramen is a window in the lateral aspect of the spinal canal where nerve roots emanate from the dural sac and leave the spinal canal through the intervertebral foramen. The anatomical relationship between the nerve roots and the intervertebral foramen and its surrounding soft tissues is very close, and stenosis of the intervertebral foramen can lead to nerve root entrapment, and it has been reported in the literature that nerve root entrapment caused by foraminal stenosis accounts for about 10% of all kinds of nerve root entrapment. Clarifying the characteristics of nerve root compression in patients with degenerative lumbar scoliosis not only helps to make a correct diagnosis, but also can determine the scope of decompression for surgery and avoid incomplete intraoperative decompression and blind expansion of decompression. In this study, we measured the lumbar Cobb angle on X-ray films, performed MSCT thin-section scanning of the lumbar spine, measured the lumbar articular eminence joint angle and vertebral rotation, and also imported the lumbar spine scan data into medical reconstruction software for 3D reconstruction of the intervertebral foramen, and measured the transverse and longitudinal diameters of the intervertebral foramina from L1 to 5 using the measurement function of the software. Through statistical analysis of the above measurement data, we explored the degenerative Through statistical analysis of the above measurements, we investigated the characteristics of imaging changes and pathogenesis of degenerative lumbar scoliosis in order to further improve the diagnosis and treatment of degenerative lumbar scoliosis. Materials and methods I. General data Sixty-nine patients were diagnosed with degenerative lumbar scoliosis from October 2006 to December 2009 after obtaining informed consent from patients attending the outpatient clinic and ward of the Department of Orthopedics of Hunan Provincial People’s Hospital. Inclusion criteria:The lumbar spine was free of congenital malformations, tuberculosis, tumors, fractures, major bone metabolic diseases and no significant scoliosis in other segments of the spine. There were 30 males and 39 females; age 50-78 years, mean 63.5±9.73 years; medical history 3 months-16 years, mean 4.2 years for the LDS group. Sixty-eight patients with non-spinal disorders admitted during the same period were in the control group.